| Identification | Back Directory | [Name]
NFAT inhibitor, Cell Permeable | [CAS]
592517-80-1 | [Synonyms]
PubChem ID: 121513885
11R-VIVIT (NFAT inhibitor)
NFAT inhibitor, Cell Permeable | [Molecular Formula]
C147H259N67O36S | [MDL Number]
MFCD34597381 | [MOL File]
592517-80-1.mol | [Molecular Weight]
3573.12 |
| Chemical Properties | Back Directory | [density ]
1.56±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
lyophilized solid | [color ]
white | [Water Solubility ]
Soluble to 1 mg/ml in water |
| Hazard Information | Back Directory | [Uses]
Use at 1 μM for preventing the activation and proliferation of T cells | [Biological Activity]
Primary Target
NFAT | [in vivo]
11R-VIVIT significantly abrogates the increased urinary albumin excretion rates, attenuates glomerular basement membrane (GBM) thickening and podocyte foot process effacement, partially restores podocyte number, inhibits NFAT2 activation and uPAR expression in glomerular podocytes[1]. | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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