| Chemical Properties | Back Directory | [density ]
1.368±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
2.837±0.10(predicted) | [color ]
White to off-white | [Sequence]
{Myr}-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Leu-Gly-Tyr-Pro-Asp-Tyr-Asp |
| Hazard Information | Back Directory | [Uses]
mSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. mSIRK disrupts the interaction between α and βγ subunits and promotes α subunit dissociation without stimulating nucleotide exchange[1]. | [References]
[1] Farida Goubaeva, et al. Stimulation of Cellular Signaling and G Protein Subunit Dissociation by G Protein βγ Subunit-binding Peptides. J Biol Chem. 2003 May 30;278(22):19634-41. DOI:10.1074/jbc.M300052200 |
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| Company Name: |
Fuan Bio
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| Tel: |
15002819872 |
| Website: |
fuanbio.com |
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