| Identification | Back Directory | [Name]
ethyl 2-(4-chlorophenyl)-5-ethoxy-4-oxazoleacetate | [CAS]
59399-41-6 | [Synonyms]
Y-9738
ethyl 2-(4-chlorophenyl)-5-ethoxy-4-oxazoleacetate
2-(4-Chlorophenyl)-5-ethoxy-4-oxazoleacetic acid ethyl ester
4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-ethoxy-, ethyl ester | [Molecular Formula]
C15H16ClNO4 | [MDL Number]
MFCD01755470 | [MOL File]
59399-41-6.mol | [Molecular Weight]
309.74 |
| Chemical Properties | Back Directory | [Boiling point ]
416.2±55.0 °C(Predicted) | [density ]
1.226±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
-1.06±0.24(Predicted) |
| Hazard Information | Back Directory | [Uses]
Y-9738 is a hypolipidemic agent. | [in vivo]
Y-9738 is a hypolipidemic agent. At 100 mg/kg Y-9738 lowers the cholesterol level by 36% and clearly diminishes the intensity of the β-lipoprotein band with a tendency for the α-lipoprotein band to be intensified. Y-9738 causes a dose-dependent decrease in serum cholesterol, triglyceride and heparin-precipitable β-lipoprotein cholesterol. Furthermore, Y-9738 reduces the intensity of the β-lipoprotein band shown by electrophoresis, and increases that of the α-lipoprotein band[1]. | [References]
[1] Kobayakawa T, et al. Experimental hyper-beta-lipoproteinemia and its amelioration by a novel hypolipidemic agent. Atherosclerosis. 1978 Jul;30(3):219-25. DOI:10.1016/0021-9150(78)90048-5 |
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