| Identification | Back Directory | [Name]
[LEU13]-MOTILIN PORCINE | [CAS]
59530-69-7 | [Synonyms]
KW 5139
13-Leu-motilin
[LEU13]-MOTILIN PORCINE
Motilin (swine), 13-L-leucine-
(LEU13)-MOTILIN (HUMAN, PORCINE)
(Leu??)-Motilin (human, porcine) trifluoroacetate salt
PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-LEU-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN
H-PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-LEU-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN-OH | [Molecular Formula]
C121H190N34O35 | [MDL Number]
MFCD00133964 | [MOL File]
59530-69-7.mol | [Molecular Weight]
2681.01 |
| Chemical Properties | Back Directory | [density ]
1.47±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [storage temp. ]
−20°C | [Sequence]
Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln |
| Hazard Information | Back Directory | [Uses]
[Leu13]-Motilin (KW-5139) is a motilin analogue. [Leu13]-Motilin stimulates gastrointestinal motility in the rabbit. [Leu13]-Motilin causes concentration-dependent contractions of the gastric antrum, duodenum, jejunum, ileum and the descending colon in vitro[1]. | [References]
[1] Kitazawa T, et al. Stimulating action of KW-5139 (Leu13-motilin) on gastrointestinal motility in the rabbit. Br J Pharmacol. 1994 Jan;111(1):288-94. DOI:10.1111/j.1476-5381.1994.tb14058.x |
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