| Identification | Back Directory | [Name]
N-Acetyl-L-cysteine ethyl ester | [CAS]
59587-09-6 | [Synonyms]
NACET
101242
Acetylcysteine Impurity H
ethyl acetyl-L-cysteinate
Ethyl N-acetyl-L-cysteinate
N-Acetylcysteine ethylester
N-Acetyl-L-cysteine ethyl ester
L-Cysteine, N-acetyl-, ethyl ester
N-ethyl cool-L-cysteine ethyl ester
-Ethyl 2-acetamido-3-mercaptopropanoate
(R)-ethyl 2-acetaMido-3-Mercaptopropanoate
(R)-Methyl 2-acetaMido-3-Mercaptopropanoate
ethyl (2R)-2-acetamido-3-sulfanylpropanoate
NACET
Synonyms: N-Acetyl-L-cysteine ethyl ester
2-acetamido-3-mercaptopropanoic acid ethyl ester | [EINECS(EC#)]
-0 | [Molecular Formula]
C7H13NO3S | [MDL Number]
MFCD09954466 | [MOL File]
59587-09-6.mol | [Molecular Weight]
191.25 |
| Chemical Properties | Back Directory | [Melting point ]
44.1-44.5 °C | [Boiling point ]
337.6±32.0 °C(Predicted) | [density ]
1.138±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
9.17±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; ). It has enhanced cell permeability in isolated perfused rat liver compared to NAC. N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; ) in rats. |
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