| Identification | Back Directory | [Name]
L-Lysine, mono[3-chloro-4-(2-propenyloxy)benzeneacetate] (9CI) | [CAS]
59960-34-8 | [Synonyms]
Alclofenac lysinate
L-Lysine, mono[3-chloro-4-(2-propenyloxy)benzeneacetate] (9CI) | [Molecular Formula]
C17H25ClN2O5 | [MOL File]
59960-34-8.mol | [Molecular Weight]
372.85 |
| Hazard Information | Back Directory | [Description]
Alclofenac is an anti-inflammatory agent used in the treatment of rheumatoid arthritis; acts also as an analgesic and an antipyretic. | [Uses]
Alclofenac lysinate is a non-steroidal anti-inflammatory agent (NSAID). Alclofenac lysinate is a prostaglandin H2 synthase inhibitor. Alclofenac lysinate can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research[1][2]. | [References]
[1] R N Brogden, et al. Alclofenac: a review of its pharmacological properties and therapeutic efficacy in rheumatoid arthritis and allied rheumatic disorders. Drugs. 1977 Oct;14(4):241-59. DOI:10.2165/00003495-197714040-00001
[2] B S Selinsky, et al. Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. Biochemistry. 2001 May 1;40(17):5172-80. DOI:10.1021/bi010045s |
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