ChemicalBook--->CAS DataBase List--->600-57-7

600-57-7

600-57-7 Structure

600-57-7 Structure
IdentificationBack Directory
[Name]

11BETA-HYDROXYPROGESTERONE
[CAS]

600-57-7
[Synonyms]

21-deoxycorticosterone
11B-HYDROXYPROGESTERONE
11β-hydroxyprogesterone
HYDROXYPROGESTERONE, 11B-
11BETA-HYDROXYPROGESTERONE
4-PREGNEN-11BETA-3,20-DIONE
4-PREGNEN-11BETA-OL-3,20-DIONE
11beta-Hydroxyprogesterone, >98%
Progesterone 11beta-Hydroxy Impurity
11-beta-hydroxy-pregn-4-ene-20-dione
11-beta-hydroxypregn-4-ene-3,20-dione
11-BETA-HYDROXY-4-PREGNENE-3,20-DIONE
11-hydroxy-20-dion(11-beta)-pregn-4-ene-
Pregn-4-ene-3,20-dione,11-hydroxy-, (11b)-
Pregn-4-ene-3,20-dione, 11-hydroxy-, (11β)-
17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
[EINECS(EC#)]

209-995-8
[Molecular Formula]

C21H30O3
[MDL Number]

MFCD00064137
[MOL File]

600-57-7.mol
[Molecular Weight]

330.46
Chemical PropertiesBack Directory
[Melting point ]

181~184℃
[Boiling point ]

487.4±45.0 °C(Predicted)
[density ]

1.15±0.1 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

14.52±0.70(Predicted)
[color ]

White to Off-White
[Water Solubility ]

30.84mg/L(37 ºC)
Hazard InformationBack Directory
[Uses]

11β-Hydroxy Progesterone is a derivative of Progesterone (P755900) is a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.This compound is a contaminant of emerging concern (CECs).
[Definition]

ChEBI: 11beta-hydroxyprogesterone is a 11beta-hydroxy steroid that is progesterone substituted by a beta-hydroxy group at position 11. It has a role as a human metabolite and a mouse metabolite. It is functionally related to a progesterone.
[in vivo]

11β-hydroxyprogesterone causes a significant elevation in blood pressure within 3 days, an effect that persisted throughout the 14-day infusion. 11β-hydroxyprogesterone is potently hypertensinogenic in the rat and that this activity depends on an intact adrenal and at least in part on the activation of mineralocorticoid receptors[2].

[IC 50]

Human Endogenous Metabolite
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

11BETA-HYDROXYPROGESTERONE(600-57-7)1HNMR
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