| Identification | Back Directory | [Name]
Met-enkephalinamide | [CAS]
60117-17-1 | [Synonyms]
5-Methionine-enkephalin amide
L-Methioninamide, L-tyrosylglycylglycyl-L-phenylalanyl- | [Molecular Formula]
C27H36N6O6S | [MDL Number]
MFCD00076416 | [MOL File]
60117-17-1.mol | [Molecular Weight]
572.68 |
| Chemical Properties | Back Directory | [Melting point ]
142-145 °C | [Boiling point ]
1066.7±65.0 °C(Predicted) | [density ]
1.303±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
9.97±0.15(Predicted) | [Sequence]
Tyr-Gly-Gly-Phe-Met-NH2 |
| Hazard Information | Back Directory | [Uses]
[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors. | [IC 50]
δ Opioid Receptor/DOR | [References]
[1] Stiene-Martin A, et al. Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro. J Neurosci Res. 1991 Aug;29(4):538-48. DOI:10.1002/jnr.490290415
[2] Kennedy C, et al. [Met5]enkephalin acts via delta-opioid receptors to inhibit pelvic nerve-evoked contractions of cat distal colon. Br J Pharmacol. 1987 Oct;92(2):291-8. DOI:10.1111/j.1476-5381.1987.tb11323.x |
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Ontores Biotech
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www.ontoresinc.cn |
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