| Identification | Back Directory | [Name]
Benzeneacetic acid, α-[(3,5-dimethoxyphenyl)methylene]-4-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-, methyl ester, (αE)- | [CAS]
606932-81-4 | [Synonyms]
Benzeneacetic acid, α-[(3,5-dimethoxyphenyl)methylene]-4-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-, methyl ester, (αE)- | [Molecular Formula]
C28H25NO7S | [MOL File]
606932-81-4.mol | [Molecular Weight]
519.57 |
| Chemical Properties | Back Directory | [Melting point ]
126-128 °C | [Boiling point ]
706.3±60.0 °C(Predicted) | [density ]
1.308±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.32±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(E)-CLX-0921 is the E-isomer of CLX-0921 (HY-19394). CLX-0921 is an orally active PPARγ agonist with an IC50 of 1.54 μM. CLX-0921 has a potent antihyperglycemic activity, and can be used for the study of type 2 diabetes[1]. | [References]
[1] Debendranath Dey, et al. A novel peroxisome proliferator-activated gamma (PPAR gamma) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential. Metabolism. 2003 Aug;52(8):1012-8. DOI:10.1016/s0026-0495(03)00152-5 |
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