| Identification | Back Directory | [Name]
4-Hydroxyphenyl 4-Methoxyphenyl ketone | [CAS]
61002-54-8 | [Synonyms]
4-HYDROXY-4'-METHOXYBENZOPHENONE
4-HYDROXY-4'-METHOXYBENZOPHENONE
4-[(4-methoxyphenyl)carbonyl]phenol
4-Hydroxyphenyl 4-Methoxyphenyl ketone
(4-hydroxyphenyl)-(4-methoxyphenyl)methanone
Methanone, (4-hydroxyphenyl)(4-methoxyphenyl)- | [Molecular Formula]
C14H12O3 | [MDL Number]
MFCD00020168 | [MOL File]
61002-54-8.mol | [Molecular Weight]
228.24 |
| Hazard Information | Back Directory | [Uses]
4-Hydroxy-4''-methoxybenzophenone is an intermediate in the synthesis of Nitromifene Citrate (E/Z mixture) (N496700). Nitromifene Citrate s a non-steroidal estrogen antagonist. It is structurally similar to Tamoxifen (T006000) which is a selective estrogen response modifier (SERM). | [Preparation]
Preparation by reduction of 4-methoxy- 4?-nitro-benzophenone with stannous chloride and hydrochloric acid, followed by diazotization of the resulting 4-amino-4?-methoxybenzophenone and hydrolysis of the diazonium salt. |
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