| Identification | Back Directory | [Name]
N-NITROSO-N-ETHYLANILINE | [CAS]
612-64-6 | [Synonyms]
NEA
NSC 405070
Ethylnitrosoaniline
Nitrosoethylaniline
Nitrosoethylphenylamine
N-ETHYL-N-NITROSOANILINE
N-NITROSO-N-ETHYLANILINE
n-ethyl-n-nitroso-anilin
N-NITROSOETHYLPHENYLAMINE
N-Ethyl-N-phenylnitrosamine
Aniline, N-ethyl-N-nitroso-
n-ethyl-n-nitroso-benzenamin
n-ethyl-n-nitrosobenzenamine
N-ethyl-N-phenylnitrous amide
N-ethyl-N-phenyl-nitrous amide
Benzenamine,N-ethyl-N-nitroso-
1-Ethyl-2-oxo-1-phenylhydrazine
N-Ethyl-N-nitrosoaniline, N-Nitrosoethylphenylamine | [Molecular Formula]
C8H10N2O | [MDL Number]
MFCD01670254 | [MOL File]
612-64-6.mol | [Molecular Weight]
150.18 |
| Chemical Properties | Back Directory | [Appearance]
Yellow Oil | [Boiling point ]
86°C/ 1 mm | [density ]
1.0874 | [refractive index ]
1.6180 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
DMSO: 5mg/mL | [form ]
Oil | [pka]
-1.59±0.50(Predicted) | [color ]
Yellow oil | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [InChI]
InChI=1S/C8H10N2O/c1-2-10(9-11)8-6-4-3-5-7-8/h3-7H,2H2,1H3 | [InChIKey]
WXRXVZXYLBWKRG-UHFFFAOYSA-N | [SMILES]
C1(N(CC)N=O)=CC=CC=C1 | [EPA Substance Registry System]
N-Nitroso-N-ethylaniline (612-64-6) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Oil | [General Description]
Clear amber or yellow liquid. | [Air & Water Reactions]
Insoluble in water. | [Reactivity Profile]
A nitrated amine. Amines are combustible. The combustion of amines yields noxious NOx. REACTIVITY - Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups. | [Health Hazard]
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. | [Fire Hazard]
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. | [Description]
N-Nitroso-N-ethylaniline is a member of the N-nitrosamine class of compounds, which are classified as carcinogens by the Environmental Protection Agency.1 However, N-nitroso-N-ethylaniline is non-carcinogenic in a survival assay using 2FR450 Rauscher leukemia virus-infected rat embryo cultures.2 It is a synthetic intermediate in the synthesis of 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as antagonists of chemokine (C-X-C motif) receptor 2 (CXCR2).3WARNING This product is not for human or veterinary use. | [Safety Profile]
Confirmed carcinogen. Poison byingestion and intraperitoneal routes. An experimentalteratogen. Mutation data reported. Many N-nitrosocompounds are carcinogens. When heated todecomposition it emits toxic fumes of NOx. |
| Safety Data | Back Directory | [Safety Statements ]
24/25 | [RIDADR ]
2810 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29214200 | [Toxicity]
LD50 orl-rat: 180 mg/kg VOONAW 14(3),37,68 |
|
|