| Identification | Back Directory | [Name]
CBO-P11 | [CAS]
612096-46-5 | [Synonyms]
CBO-P11
CYCLO-VEGI
D-PHE-PRO(79-93)
CYCLIC(D-F-PQIMRIKPHQGQHIGE) | [Molecular Formula]
C90H140N28O22S | [MDL Number]
MFCD06411466 | [MOL File]
612096-46-5.mol | [Molecular Weight]
1998.31 |
| Chemical Properties | Back Directory | [density ]
1.506±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [Sequence]
Cyclo(Asp-Phe-Pro-Gln-Ile-Met-Arg-Ile-Lys-Pro-His-Gln-Gly-Gln-His-Ile-Gly-Glu) |
| Hazard Information | Back Directory | [Uses]
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling[1]. | [References]
[1] Stéphanie Deshayes, et al. "Click" conjugation of peptide on the surface of polymeric nanoparticles for targeting tumor angiogenesis. Pharm Res. 2011 Jul;28(7):1631-42. DOI:10.1007/s11095-011-0398-5 |
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