| Identification | Back Directory | [Name]
mycaminosyltylonolide | [CAS]
61257-02-1 | [Synonyms]
mycaminosyltylonolide
5-O-mycaminosyltylonolide
Tylonolide, 5-O-[3,6-dideoxy-3-(dimethylamino)-β-D-glucopyranosyl]- | [Molecular Formula]
C31H51NO10 | [MOL File]
61257-02-1.mol | [Molecular Weight]
597.74 |
| Chemical Properties | Back Directory | [Melting point ]
132-135 °C | [Boiling point ]
799.9±60.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.18±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis[1][2]. | [Definition]
ChEBI: A macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. | [References]
[1] Shishkina A, et al. Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. Bioconjug Chem. 2013 Nov 20;24(11):1861-9. DOI:10.1021/bc400236n
[2] Sugawara A, et al. 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity. J Antibiot (Tokyo). 2017 Jul;70(8):878-887. DOI:10.1038/ja.2017.61 |
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