| Identification | Back Directory | [Name]
4-Isobutyl-2-pyrrolidinone | [CAS]
61312-87-6 | [Synonyms]
Pregabalin Lactam
Pregabalin USP RC A
4-(2-Methylpropyl)-
Pregabalin impurity D
Pregabalin IMpurity IV
4-isobutyl-2-pyrrolidone
Pregabalin LactaM IMpurity
4-Isobutyl-2-pyrrolidinone
4-isobutylpyrrolidin-2-one
4-ISOBUTYL-2-PYRROLIDIN-1-YLNE
4-(2-Methylpropyl)-2-pyrrolidinone
4-(2-methylpropyl)pyrrolidin-2-one
2-pyrrolidinone, 4-(2-methylpropyl)-
4-isobutyl-2-pyrrolidinone(SALTDATA: FREE)
4-Isobutyl-2-pyrrolidinone (pregabalin lactaM iMpurity)
rac-Pregabalin EP Impurity A (Pregabalin Lactam Impurity) | [Molecular Formula]
C8H15NO | [MDL Number]
MFCD09864501 | [MOL File]
61312-87-6.mol | [Molecular Weight]
141.21 |
| Chemical Properties | Back Directory | [Boiling point ]
269.1±9.0 °C(Predicted) | [density ]
0.927±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
16.66±0.40(Predicted) | [color ]
Colourless to Light Yellow | [CAS DataBase Reference]
61312-87-6 |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Oil | [Uses]
Impurity in commercial preparation of Pregabalin. | [Uses]
Pregabalin (P704800) | [Uses]
Pregabalin intermediate | [Synthesis]
To 600 mL of methanol, 50.00 g of nitro compound (01), 18.04 g of NiCl2-6H2O was added; the solution was cooled down to 0°C-5°C and 18.2 g of sodium borohydride was added. After addition, the temperature was raised to 40°C-45°C and stirred for 12 hours. T |
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