| Identification | Back Directory | [Name]
Pirmenol hydrochloride | [CAS]
61477-94-9 | [Synonyms]
CI 845
Cl 845
Pimavar
Pirmavar
Ccris 5234
Pirmenol HCl
pirmenol hydrochloride
(à)-Pirmenol hydrochlorid
Pirmenol hydrochloride(cis)
Pirmenol hydrochloride, >97%
PIRMENOL HYDROCHLORIDE; CI-845; PIMENOL; PIMAVAR
4-[(2R,6S)-2,6-dimethyl-1-piperidyl]-1-phenyl-1-pyridin-2-yl-butan-1-o l hydrochloride
(+-)-cis-2,6-Dimethyl-alpha-phenyl-alpha-2-pyridyl-1-piperidinebutanol monohydrochloride
4-((2R,6S)-2,6-Dimethylpiperidin-1-yl)-1-phenyl-1-(pyridin-2-yl)butan-1-ol hydrochloride
1-Piperidinebutanol, 2,6-dimethyl-alpha-phenyl-alpha-(2-pyridyl)-, hydrochloride, Z-(+-)-
2-Pyridinemethanol, a-[3-(2,6-dimethyl-1-piperidinyl)propyl]-a-phenyl-, monohydrochloride, cis-
2-Pyridinemethanol, a-[3-(2,6-dimethyl-1-piperidinyl)propyl]-a-phenyl-, monohydrochloride, cis-(+-)-
2-Pyridinemethanol, alpha-(3-(2,6-dimethyl-1-piperidinyl)propyl)-alpha-phenyl-, monohydrochloride, Z-(+-)-
2-Pyridinemethanol, a-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-a-phenyl-, monohydrochloride, rel- (9CI)
2-Pyridinemethanol, alpha-(3-(2,6-dimethyl-1-piperidinyl)propyl)-alpha-phenyl-, monohydrochloride, cis-, (+-)- | [Molecular Formula]
C22H31ClN2O | [MDL Number]
MFCD01691662 | [MOL File]
61477-94-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
171-172 °C | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO : ≥ 28 mg/mL (74.68 mM) | [form ]
Solid | [color ]
White to yellow |
| Hazard Information | Back Directory | [Description]
Pirrnenol hydrochloride is a long-lasting Class la antiarrhythmic agent introduced
in Japan in 1994. The spectrum of antiarrhythmic activity of pirmenol includes atrial
and ventricular arrhythmias of diverse etiology. In clinical trials, pirmenol was found
effective in the short- and mid-term treatment of chronic premature ventricular
beats, with or without underlying heart disease. In patients with supraventricular
tachycardia, a single oral dose of pirmenol was highly effective in suppressing
induction of tachycardia with adequate hemodynamic tolerance. Since pirmenol is
highly effective by both intravenous and oral routes, it enables immediate
suppression, prevention, or termination of cardiac arrhythmias and facilitates the
transition to oral prophylactic therapy. | [Originator]
Warner-Lamber (U.S.A.) | [Uses]
Cardiac depressant (anti-arrhythmic). | [Brand name]
Pirmavar (Parke-Davis);Plmenol. | [storage]
Store at -20°C | [Toxics Screening Level]
The initial threshold screening level (ITSL) for pirmenol is 3 μg/m3 baaed on an annual averaging time. |
|
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
| Company Name: |
InvivoChem
|
| Telephone: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|