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615273-95-5

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615273-95-5 Structure

615273-95-5 Structure
IdentificationBack Directory
[Name]

4-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]morpholine
[CAS]

615273-95-5
[Synonyms]

WAY-327111
EP2 receptor antagonist-2
4-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]morpholine
Morpholine, 4-[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]-
[Molecular Formula]

C15H14F3N3O
[MOL File]

615273-95-5.mol
[Molecular Weight]

309.29
Chemical PropertiesBack Directory
[Boiling point ]

451.8±55.0 °C(Predicted)
[density ]

1.299±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

1.48±0.50(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

EP2 receptor antagonist-2 (CID891729) is an antagonist of EP2 receptor. EP2 receptor antagonist-2 inhibits the EP2 receptor activation induced by PGE2. EP2 receptor antagonist-2 also suppresses lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA)[1].
[IC 50]

EP
[References]

[1] Jiang J, et al. Discovery of 2-Piperidinyl Phenyl Benzamides and Trisubstituted Pyrimidines as Positive Allosteric Modulators of the Prostaglandin Receptor EP2. ACS Chem Neurosci. 2018 Apr 18;9(4):699-707. DOI:10.1021/acschemneuro.7b00486
Spectrum DetailBack Directory
[Spectrum Detail]

4-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]morpholine(615273-95-5)1HNMR
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