| Identification | Back Directory | [Name]
1-methyl-2-[1-[4-(2-methylpropyl)phenyl]ethyl]benzimidazole | [CAS]
615281-26-0 | [Synonyms]
1-methyl-2-[1-[4-(2-methylpropyl)phenyl]ethyl]benzimidazole
1H-Benzimidazole, 1-methyl-2-[1-[4-(2-methylpropyl)phenyl]ethyl]-
1-methyl-2-{1-[4-(2-methylpropyl)phenyl]ethyl}-1H
-1,3-benzodiazole | [Molecular Formula]
C20H24N2 | [MDL Number]
MFCD03660794 | [MOL File]
615281-26-0.mol | [Molecular Weight]
292.42 |
| Hazard Information | Back Directory | [Uses]
NPD8790 is a species selective mitochondrial respiratory complex I inhibitor with an IC50?of 2.4?μM for C. elegans complex I. NPD8790 is more selective for nematode species mitochondria than human, bovine, and mouse mitochondria. NPD8790 is an anthelmintic that kills adult soil-transmitted helminths[1]. | [References]
[1] Taylor Davie, et al. Identification of a family of species-selective complex I inhibitors as potential anthelmintics. Nat Commun. 2024 May 8;15(1):3367. DOI:10.1038/s41467-024-47331-3 |
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