| Identification | Back Directory | [Name]
WS | [CAS]
615538-48-2 | [Synonyms]
WS
DC4
MFAT
AWAT2
DGAT2L4
Acyl-CoA wax alcohol acyltransferase 2
ANTI-AWAT2 (C-TERM) antibody produced in rabbit
1H-Indole-2-carboxamide, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-(phosphonooxy)-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-5-yl]-5-[(3-mercapto-1-oxopropyl)amino]- | [Molecular Formula]
C34H29ClN5O7PS | [MDL Number]
MFCD34469689 | [MOL File]
615538-48-2.mol | [Molecular Weight]
718.12 |
| Hazard Information | Back Directory | [Uses]
DC4, an ADC cytotoxin, can be used in the synthesis of antibody-drug conjugate (ADC). DC4 can be used for the targeted treatment of cancer[1]. | [References]
[1] Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82. DOI:10.1021/jm201284m |
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