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61638-08-2

61638-08-2 Structure

61638-08-2 Structure
IdentificationBack Directory
[Name]

ALEPH (hydrochloride)
[CAS]

61638-08-2
[Synonyms]

ALEPH (hydrochloride)
Benzeneethanamine, 2,5-dimethoxy-α-methyl-4-(methylthio)-, hydrochloride (1:1)
[Molecular Formula]

C12H19NO2S.ClH
[MOL File]

61638-08-2.mol
[Molecular Weight]

277.81
Chemical PropertiesBack Directory
[Melting point ]

200-202 °C
[solubility ]

DMSO: soluble
Hazard InformationBack Directory
[Uses]

ALEPH (hydrochloride) is the h5-HT2A and h5-HT2B partial agonist with the EC50 values of 10.3 nM and 19.2 nM, respectively. ALEPH (hydrochloride) causes head twitch response in mice (ED50: 0.80 mg/kg)[1].
[IC 50]

Human 5-HT2A Receptor; human 5-HT2B Receptor
[References]

[1] Halberstadt AL, et al. Use of the head-twitch response to investigate the structure-activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines. Psychopharmacology (Berl). 2023 Jan;240(1):115-126. DOI:10.1007/s00213-022-06279-2
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