| Identification | Back Directory | [Name]
ALEPH (hydrochloride) | [CAS]
61638-08-2 | [Synonyms]
ALEPH (hydrochloride) Benzeneethanamine, 2,5-dimethoxy-α-methyl-4-(methylthio)-, hydrochloride (1:1) | [Molecular Formula]
C12H19NO2S.ClH | [MOL File]
61638-08-2.mol | [Molecular Weight]
277.81 |
| Hazard Information | Back Directory | [Uses]
ALEPH (hydrochloride) is the h5-HT2A and h5-HT2B partial agonist with the EC50 values of 10.3 nM and 19.2 nM, respectively. ALEPH (hydrochloride) causes head twitch response in mice (ED50: 0.80 mg/kg)[1]. | [IC 50]
Human 5-HT2A Receptor; human 5-HT2B Receptor | [References]
[1] Halberstadt AL, et al. Use of the head-twitch response to investigate the structure-activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines. Psychopharmacology (Berl). 2023 Jan;240(1):115-126. DOI:10.1007/s00213-022-06279-2 |
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