ChemicalBook--->CAS DataBase List--->61641-47-2

61641-47-2

61641-47-2 Structure

61641-47-2 Structure
IdentificationBack Directory
[Name]

5(R)-HETE
[CAS]

61641-47-2
[Synonyms]

5(R)-HETE
KGIJOOYOSFUGPC-CABOLEKPSA-N
5R-HYDROXY-6E,8Z,11Z,14Z-EICOSATETRAENOIC ACID
(-)-5(R)-HYDROXY-(6E,8Z,11Z,14Z)-*EICOSA TETRAENOIC
6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (5R,6E,8Z,11Z,14Z)-
[Molecular Formula]

C20H32O3
[MDL Number]

MFCD00079359
[MOL File]

61641-47-2.mol
[Molecular Weight]

320.47
Chemical PropertiesBack Directory
[Boiling point ]

487.7±45.0 °C(Predicted)
[density ]

0.984±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
[pka]

4.67±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)
GHS02
[Signal word ]

Danger
Hazard InformationBack Directory
[Uses]

5(R)-HETE is a lipoxygenase product of arachidonic acid. 5(R)-HETE is an inducer of neutrophil migration through endothelial and epithelial barriers. 5(R)-HETE is important in mediating lung inflammatory processes[1].
[Definition]

ChEBI: 5R-HETE is a hydroxy fatty acid and a polyunsaturated fatty acid.
[References]

[1] D B Bittleman, et al. 5-Hydroxyeicosatetraenoic acid (HETE)-induced neutrophil transcellular migration is dependent upon enantiomeric structure. Am J Respir Cell Mol Biol. 1995 Mar;12(3):260-7. DOI:10.1165/ajrcmb.12.3.7873191
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