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61642-40-8

61642-40-8 Structure

61642-40-8 Structure
IdentificationBack Directory
[Name]

12-ALPHA-HYDROXYSTEROID DEHYDROGENASE
[CAS]

61642-40-8
[Synonyms]

12ALPHA-HSDH
EC 1.1.1.176
FromClostridiumspec.
12α-hydroxysteroid dehydrogenase
12-ALPHA-HYDROXYSTEROID DEHYDROGENASE
12ALPHA-HYDROXYSTEROID:NADP+-OXIDOREDUCTASE
12A-HYDROXYSTEROID DEHYDROGENASE FROM*BA CILLUS SPHA
12α-Hydroxysteroid Dehydrogenase from Clostridium sp.
Native Bacillus sphaericus 12α-Hydroxysteroid Dehydrogenase
12α-Hydroxysteroid Dehydrogenase from Bacillus sphaericus
[MDL Number]

MFCD00166470
Chemical PropertiesBack Directory
[Melting point ]

206-210 °C
[storage temp. ]

−20°C
Hazard InformationBack Directory
[Uses]

12α-Hydroxysteroid dehydrogenase, bacillus sphaericus is a dehydrogenase expressed in Bacillus sphaericus. 12α-Hydroxysteroid dehydrogenase, bacillus sphaericus is NAD-dependent and is active on both bound and unbound bile salts. This enzyme can be used to measure the concentration of 12α-hydroxy bile acids in serum[1].
[References]

[1] Macdonald IA, et al. 3alpha-, 7alpha- and 12alpha-hydroxysteroid dehydrogenase activities from Clostridium perfringens. Biochim Biophys Acta. 1976 Nov 19;450(2):142-53. DOI:10.1016/0005-2760(76)90086-2
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