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61848-66-6

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61848-66-6 Structure

61848-66-6 Structure
IdentificationBack Directory
[Name]

Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [sp-4-2-(1R-trans)]-
[CAS]

61848-66-6
[Synonyms]

Nsc265460
Nsc 265460
Oxaliplatin System Suitability (25 mg)
Dichloro(1R,2R-cyclohexanediammine)platinum(II)
Cis-Dichloro-(1R)-trans-1,2-cyclohexanediaMine platinuM(Ⅱ)
Cis-Dichloro-(1R)-trans-1,2-cyclohexanediamine platinum(Ⅱ)
Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, (sp-4-2-(1R-trans))-
Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [sp-4-2-(1R-trans)]-
[SP-4-2-(1R-trans)]-(1,2-CyclohexanediaMine-N,N') DichloridoplatinuM(II)
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N') dichlorideplatinum(II)
Oxaliplatin System Suitability ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N'') dichloridoplatinu (1481306)
Oxaliplatin System Suitability (25 mg) ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N') dichloridoplatinum(II))
[Molecular Formula]

C6H12Cl2N2Pt
[MDL Number]

MFCD00058826
[MOL File]

61848-66-6.mol
[Molecular Weight]

378.157
Chemical PropertiesBack Directory
[Melting point ]

>256°C (dec.)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly)
[form ]

Solid
[color ]

Yellow
[Major Application]

pharmaceutical (small molecule)
[InChI]

InChI=1/C6H12N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-8H,1-4H2;2*1H;/q-2;;;+4/p-2/t5-,6-;;;/s3
[InChIKey]

UUERTZXRKZEANK-SIGUBHPQNA-L
[SMILES]

[Cl-][Pt+2]1(N[C@]2([H])CCCC[C@@]2([H])N1)[Cl-] |&1:3,9,r|
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H319-H340-H351-H360D-H372
[Precautionary statements ]

P202-P260-P264-P270-P305+P351+P338-P308+P313
[RIDADR ]

UN 3467 6.1 / PGIII
[WGK Germany ]

WGK 3
[HS Code ]

2843900000
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Carc. 2
Eye Irrit. 2
Muta. 1B
Repr. 1B
STOT RE 1
Hazard InformationBack Directory
[Uses]

[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) dichloridoplatinum(II) is an impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
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