| Identification | Back Directory | [Name]
DESOXYPEGANINE HYDROCHLORIDE | [CAS]
61939-05-7 | [Synonyms]
DEOXYPEGANINE HCL
Deoxyvasicine HCl
DESOXYPEGANINE HCL
pegenehydrochloride
deoxypeganinehydrochloride
deoxyvasicinehydrochloride
deoxy-vasicinhydrochloride
DESOXYPEGANINE HYDROCHLORIDE
Vasicine, deoxy-, hydrochloride
1H,2H,3H,9H-pyrrolo[2,1-b]quinazoline hydrochloride
1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline hydrochloride
1,2,3,8-Tetrahydropyrroll[2,1-b]-chynazolina chlorohydrate
1-b)quinazoline,1,2,3,9-tetrahydro-pyrrolo(monohydrochloride
Pyrrolo(2,1-B)quinazoline, 1,2,3,9-tetrahydro-, monohydrochloride | [Molecular Formula]
C11H13ClN2 | [MDL Number]
MFCD00155365 | [MOL File]
61939-05-7.mol | [Molecular Weight]
208.69 |
| Hazard Information | Back Directory | [Uses]
Desoxypeganine Hydrochloride is a naturally occurring alkaloid that is a cholinesterase inhibitor. | [in vivo]
Desoxypeganine hydrochloride (10-30 mg/kg, gavage, once daily for 16 days) reduced ethanol intake and ethanol preference dose-dependently[1]. | Animal Model: | Female Alko alcohol (AA) rats (Thirty eight adult)[1] | | Dosage: | 10, 20, 30 mg/kg | | Administration: | Gavage, once daily in a volume of 10 ml/kg at 6:00 pm, for 16 days | | Result: | Abolished ethanol preference. |
| [IC 50]
BChE: 2 μM (IC50); AChE: 17 μM (IC50); MAO-A: 2 μM (IC50) |
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