| Identification | Back Directory | [Name]
DSP 4 | [CAS]
62078-98-2 | [Synonyms]
az-Dsp 4
UNII-PQ1P7JP5C1
Benzenemethanamine, 2-bromo-N-(2-chloroethyl)-N-ethyl- | [Molecular Formula]
C11H15BrClN | [MDL Number]
MFCD00600075 | [MOL File]
62078-98-2.mol | [Molecular Weight]
276.603 |
| Hazard Information | Back Directory | [Hazard]
A poison. | [Uses]
DSP 4 Free base is a selective neurotoxin that targets noradrenergic neurons in the locus coeruleus noradrenergic system. DSP 4 Free base possesses the unique ability to cross the blood–brain barrier. DSP 4 Free base cyclizes to form a reactive aziridinium derivative that accumulates in noradrenergic neurons. | [References]
[1] Neurotoxicity of N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride (DSP 4) on noradrenergic neurons is mimicked by its cyclic aziridinium derivative |
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