| Identification | Back Directory | [Name]
AC-PHE-PHE-HIS-OME | [CAS]
62087-96-1 | [Synonyms]
zami420
Triletide
AC-PHE-PHE-HIS-OME
TRIPEPTIDE ZAMI 420
ACETYL-L-PHENYLALANYL-L-PHENYALANYL-L-HISTIDINE METHYL ESTER
N-Acetyl-L-phenylalanyl-L-phenylalanyl-L-histidine methyl ester
L-Histidine, N-acetyl-L-phenylalanyl-L-phenylalanyl-, methyl ester | [EINECS(EC#)]
263-401-1 | [Molecular Formula]
C27H31N5O5 | [MDL Number]
MFCD00153590 | [MOL File]
62087-96-1.mol | [Molecular Weight]
505.57 |
| Hazard Information | Back Directory | [Uses]
Triletide is a thromboxane A2 antagonist with good oral absorption activity. The biotransformation of Triletide mainly includes the formation of demethyl, deacetyl, demethyl-deacetyl and hydroxy derivatives. The distribution half-life of Triletide is about 1 hour, and the elimination half-life is about 5 hours[1]. | [References]
[1] Preliminary human pharmacokinetics of triletide PMID:4059299 |
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