| Identification | Back Directory | [Name]
dihydrocarminomycin | [CAS]
62182-86-9 | [Synonyms]
RP-32999
Carminomycinol
Antibiotic RP-32999
dihydrocarminomycin
Dihydrokarminomycin
10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(1-hydroxyethyl)-5,12-naphthacenedione
5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(1-hydroxyethyl)- | [Molecular Formula]
C26H29NO10 | [MOL File]
62182-86-9.mol | [Molecular Weight]
515.52 |
| Hazard Information | Back Directory | [Description]
Dihydrocarminomycin is an anthracycline antibiotic. | [Uses]
13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity[1][2]. | [References]
[1] Yoshimoto A, et al. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. II. New anthracycline metabolites produced by a blocked mutant strain RPM-5. J Antibiot (Tokyo). 1993 Jan;46(1):56-64. DOI:10.7164/antibiotics.46.56
[2] Poteshnykh AV, et al. Determination of carminomycin and its basic metabolite 13-dihydrocarminomycin by a highly efficient liquid chromatographic method with a fluorescent detector. Antibiotiki. 1982 Nov;27(11):820-3. PMID:7181464 |
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