| Identification | Back Directory | [Name]
morusin | [CAS]
62596-29-6 | [Synonyms]
Moracin
Morusin?, >99%
Mulberrochromene
morusin 62596-29-6
Morusin(Mulberrochromene)
2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one
2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methylbut-2-en-1-yl)pyrano[2,3-f]chromen-4(8H)-one
4H,8H-Benzo(1,2-B:3,4-B')dipyran-4-one,2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-diMethyl-3-(3-Methyl-2-butenyl)
2-(2,4-Dihydroxyphenyl)-3-(3-methyl-2-butenyl)-5-hydroxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-buten-1-yl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one, 2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-buten-1-yl)- | [EINECS(EC#)]
300-006-7 | [Molecular Formula]
C25H24O6 | [MDL Number]
MFCD09953814 | [MOL File]
62596-29-6.mol | [Molecular Weight]
420.459 |
| Chemical Properties | Back Directory | [Melting point ]
232-235℃ | [Boiling point ]
656.7±55.0 °C(Predicted) | [density ]
1.303 | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
DMF: 20mg/mL; DMF:PBS (pH 7.2) (1:3): 0.25mg/mL; DMSO: 10mg/mL; Ethanol: 15mg/mL | [form ]
powder | [pka]
6.55±0.60(Predicted) | [color ]
Beige-orange | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Chemical Properties]
Soluble in DMSO and hot methanol, insoluble in petroleum ether and chloroform. Derived from the root bark of Morus alba L., a plant of the Moraceae family, after removing the yellow-brown rough bark. | [Uses]
Morusin is an inhibitor of human cervical cancer stem cell growth, attenuating NF-kB activity, and initiating apoptosis. | [Definition]
ChEBI: An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8. | [in vivo]
Morusin retards the growth of breast cancer significantly. Mean tumor weight of the control mice is 1.14±0.30 g, and those of the mice administrated with 5 and 10 mg/kg of morusin are 0.61±0.23 and 0.41±0.10 g, respectively, tumor inhibitory rates are 46.5 %, and 64.1 %, respectively[1]. | [IC 50]
p65; STAT3 |
|
|