| Identification | Back Directory | [Name]
Tilisolol HCl | [CAS]
62774-96-3 | [Synonyms]
N 696
Selecal
Tilisolol HCl
trade name Selecal
tilisolol hydrochloride
Tilisolol, trade name Selecal
4-(3-(tert-ButylaMino)-2-hydroxypropoxy)-2-Methylisoquinolin-1(2H)-one hydrochloride
1(2H)-Isoquinolinone, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-2-methyl-, monohydrochloride (9CI) | [MDL Number]
MFCD00896575 | [MOL File]
62774-96-3.mol |
| Hazard Information | Back Directory | [Description]
Tilisolol hydrochloride is a long acting vasodilating beta-blocker useful in the
treatment of hypertension and angina. It is also reported to have antiarrhythmic
properties. Due to its relatively long half-life, tilisolol hydrochloride is suitable for
once a day dosing. It is currently being investigated as an antiglaucoma agent. | [Originator]
Nisshin Flour Milling (Japan) | [Definition]
ChEBI: Tilisolol hydrochloride is a member of isoquinolines. | [Brand name]
Daim; Selecal |
| Safety Data | Back Directory | [Toxicity]
LD50 in male, female mice and rats (mg/kg): 1393, 1290, 145, 188 orally; 1219, 1245, 176, 169 s.c.; 578, 557, 39.5, 29.2 i.p.; 74.3, 104.7, 75.8, 38.1 i.v. (Kawase) |
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