| Identification | Back Directory | [Name]
H-YC DEHFC GAMMA-OH, CYCLIC | [CAS]
629628-53-1 | [Synonyms]
KP7-6
H-YC DEHFC GAMMA-OH, CYCLIC | [Molecular Formula]
C48H56N10O15S2 | [MDL Number]
MFCD09037529 | [MOL File]
629628-53-1.mol | [Molecular Weight]
1077.15 |
| Chemical Properties | Back Directory | [Boiling point ]
1641.355±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.548±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
3.053±0.10(predicted) | [color ]
White to off-white | [Sequence]
Tyr-Cys-Asp-Glu-His-Phe-Cys-Tyr (Disulfide bridge:Cys2-Cys7) |
| Hazard Information | Back Directory | [Uses]
Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury[1][2]. | [References]
[1] Zhang S, et al. Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes. 2008 Feb;57(2):348-56. DOI:10.2337/db07-0849
[2] Hasegawa A, et al. Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6599-604. DOI:10.1073/pnas.0401597101 |
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| Company Name: |
Fuan Bio
|
| Tel: |
15002819872 |
| Website: |
fuanbio.com |
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