| Identification | Back Directory | [Name]
6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE, 99 | [CAS]
63283-42-1 | [Synonyms]
SalsolidineHCl
6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolinium chloride
1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylisoquinolinehydrochloride
1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-isoquinolinhydrochloride
6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE, 99 | [Molecular Formula]
C12H18ClNO2 | [MDL Number]
MFCD00050647 | [MOL File]
63283-42-1.mol | [Molecular Weight]
243.73 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline powder | [Uses]
Salsolidine hydrochloride, a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitive MAO A (monoamine oxidase A) inhibitor. | [References]
[1] Bembenek ME, et al. Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines. J Med Chem. 1990 Jan;33(1):147-52. DOI:10.1021/jm00163a025
[2] Airaksinen MM, et al. Binding of beta-carbolines and tetrahydroisoquinolines by opiate receptors of the delta-type. Acta Pharmacol Toxicol (Copenh). 1984 Nov;55(5):380-5. DOI:10.1111/j.1600-0773.1984.tb01998.x
[3] Tundis R, et al. A potential role of alkaloid extracts from Salsola species (Chenopodiaceae) in the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2009 Jun;24(3):818-24. DOI:10.1080/14756360802399662 |
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