| Identification | Back Directory | [Name]
L-Serine, butanoate (ester) | [CAS]
63321-66-4 | [Synonyms]
L-Serine, O-(1-oxobutyl)-
L-Serine, butanoate (ester) | [Molecular Formula]
C7H13NO4 | [MOL File]
63321-66-4.mol | [Molecular Weight]
175.18 |
| Chemical Properties | Back Directory | [Boiling point ]
318.5±37.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
1.89±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SerBut is a serine conjugated butyrate prodrug with oral activity. SerBut has anti-inflammatory activity[1]. | [in vivo]
SerBut (25 mg orally, once daily starting at 14 days) significantly inhibits arthritis in mice in the CAIA model [1].
| [References]
[1] Cao S, et al. A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nat Biomed Eng. 2024 Apr 1. DOI:10.1038/s41551-024-01190-x |
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