| Identification | Back Directory | [Name]
TANDEM | [CAS]
63478-55-7 | [Synonyms]
TANDEM (quinoxaline)
Des-N-tetramethyltriostin a
L-Valine, N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-L-cysteinyl-, bimol. lactone, cyclic disulfide
L-Valine, N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-L-cysteinyl-, bimol. (4-1'),(4'-1)-dilactone, cyclic (3-3')-disulfide | [Molecular Formula]
C46H54N12O12S2 | [MOL File]
63478-55-7.mol | [Molecular Weight]
1031.13 |
| Hazard Information | Back Directory | [Description]
TANDEM (quinoxaline) is a synthetic analog of quinoxaline antibiotics. | [Uses]
TANDEM (Des-N-tetramethyltriostin A) is a synthetic antibiotic drug that has the activity of inhibiting the growth of tumor cells. TANDEM can be used in combination with chemotherapy to enhance the inhibitory effect. TANDEM has shown significant inhibitory effects on a variety of cancer cell lines in in vitro experiments. The structure of TANDEM allows it to effectively target tumor cells during the inhibition process. TANDEM's mechanism of action involves interfering with cell proliferation and survival pathways[1]. | [References]
[1] The short-term safety and efficacy of TANDEM microspheres of various sizes and doxorubicin loading concentrations for hepatocellular carcinoma treatment DOI:10.1038/s41598-021-91021-9 |
|
|