| Identification | Back Directory | [Name]
C3A (70-77) | [CAS]
63555-63-5 | [Synonyms]
C3a
ASHLGLAR
C3A (70-77)
complement 3a (70-77)
Complement C3a, (70-77)
ALA-SER-HIS-LEU-GLY-LEU-ALA-ARG
ANAPHYLATOXIN C3A FRAGMENT 70-77
H-ALA-SER-HIS-LEU-GLY-LEU-ALA-ARG-OH
alanine-serine-histidine-leucine-glycine-leucine-alanine-
L-Arginine, L-alanyl-L-seryl-L-histidyl-L-leucylglycyl-L-leucyl-L-alanyl-
C3a (70-77) trifluoroacetate salt H-Ala-Ser-His-Leu-Gly-Leu-Ala-Arg-OH trifluoroacetate salt | [Molecular Formula]
C35H61N13O10 | [MDL Number]
MFCD00133055 | [MOL File]
63555-63-5.mol | [Molecular Weight]
823.94 |
| Chemical Properties | Back Directory | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Soluble in DMSO | [pka]
3.34±0.10(Predicted) | [Sequence]
Ala-Ser-His-Leu-Gly-Leu-Ala-Arg |
| Hazard Information | Back Directory | [Uses]
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a. | [Biological Activity]
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a and exhibits C3a specificity and 1 to 2% biological activity. | [in vitro]
The direct interaction of C3a(70-77) with human mononuclear leukocytes in culture results in a concentration-dependent inhibition of the generation of LIF evoked by mitogens and by the antigen SK-SD. | [target]
| [storage]
Store at -20°C | [References]
[1] Payan DG, et al. Modulation of human lymphocyte function by C3a and C3a(70-77). J Exp Med. 1982 Sep 1;156(3):756-65. DOI:10.1084/jem.156.3.756
[2] Caporale LH, et al. The active site of C3a anaphylatoxin. J Biol Chem. 1980 Nov 25;255(22):10758-63. PMID:6968751 |
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