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637-21-8

637-21-8 Structure

637-21-8 Structure
IdentificationBack Directory
[Name]

HOMATROPINE HYDROCHLORIDE
[CAS]

637-21-8
[Synonyms]

homatropineHCl
Homatropinhydrochlorid
HOMATROPINE HYDROCHLORIDE
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate hydrochloride
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-ethanoate hydrochloride
2-hydroxy-2-phenyl-acetic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride
[EINECS(EC#)]

211-280-0
[Molecular Formula]

C16H22ClNO3
[MDL Number]

MFCD00050613
[MOL File]

637-21-8.mol
[Molecular Weight]

311.8
Chemical PropertiesBack Directory
[Melting point ]

226 °C
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Merck ]

14,4730
[InChI]

InChI=1S/C4H3ClF4O2/c1-11-2(10)3(6,7)4(5,8)9/h1H3
[InChIKey]

FRMDDIJBLQNNTC-RDYJJYPNSA-N
[SMILES]

Cl.N1([C@@H]2C[C@H](C[C@H]1CC2)OC(=O)C(O)c3ccccc3)C
[CAS DataBase Reference]

637-21-8
Safety DataBack Directory
[RIDADR ]

UN 1544 6.1/PG III
[WGK Germany ]

WGK 3
[HS Code ]

2939.79.0000
[HazardClass ]

6.1
[PackingGroup ]

III
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs[1].
[References]

[1] Gore A, et al. Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats. Toxicol Sci. 2012 Apr;126(2):515-24. DOI:10.1093/toxsci/kfs009
Spectrum DetailBack Directory
[Spectrum Detail]

HOMATROPINE HYDROCHLORIDE(637-21-8)MS
HOMATROPINE HYDROCHLORIDE(637-21-8)1HNMR
HOMATROPINE HYDROCHLORIDE(637-21-8)13CNMR
HOMATROPINE HYDROCHLORIDE(637-21-8)IR1
HOMATROPINE HYDROCHLORIDE(637-21-8)IR2
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