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6381-55-1

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6381-55-1 Structure

6381-55-1 Structure
IdentificationBack Directory
[Name]

4,6-DIPHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2-THIONE
[CAS]

6381-55-1
[Synonyms]

KKII5
BUTTPARK 116\40-25
4,6-diphenyl-3,4-dihydro-1H-pyrimidine-2-thione
4,6-Diphenyl-3,4-dihydropyrimidine-2(1H)-thione
diphenyl-4,6 tetrahydro-1,2,3,4 thio-2 pyrimidine
2(1H)-Pyrimidinethione, 3,4-dihydro-4,6-diphenyl-
4,6-DIPHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2-THIONE
4,6-DIPHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2-THIONE 97%
4,6-DIPHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2-THIONE ISO 9001：2015 REACH
[Molecular Formula]

C16H14N2S
[MDL Number]

MFCD00052358
[MOL File]

6381-55-1.mol
[Molecular Weight]

266.36
Chemical PropertiesBack Directory
[Melting point ]

181-183°C
[form ]

Solid
[color ]

White to off-white
[Sensitive ]

Air Sensitive
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P280a-P304+P340-P305+P351+P338-P405-P501a
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36/37/39
Hazard InformationBack Directory
[Uses]

KKII5 is a potent Lipoxygenase (LOX-1) inhibitor with an IC50 of 19 μM. KKII5 inhibits lipid peroxidation[1].
[References]

[1] Georgiou N, et al. Thiocarbohydrazone and Chalcone-Derived 3,4-Dihydropyrimidinethione as Lipid Peroxidation and Soybean Lipoxygenase Inhibitors. ACS Omega. 2023 Mar 21;8(13):11966-11977. DOI:10.1021/acsomega.2c07625
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