| Identification | Back Directory | [Name]
CID-2011756,5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide | [CAS]
638156-11-3 | [Synonyms]
CID 2011756
CID-2011756, >97%
CID-2011756, >=98%
CID2011756; CID-2011756
5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide
5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide
5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
2-Furancarboxamide, 5-(3-chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-
CID-2011756,5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide | [EINECS(EC#)]
804-083-1 | [Molecular Formula]
C22H21ClN2O3 | [MDL Number]
MFCD04094273 | [MOL File]
638156-11-3.mol | [Molecular Weight]
396.87 |
| Chemical Properties | Back Directory | [Boiling point ]
491.0±45.0 °C(Predicted) | [density ]
1.297±0.06 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: soluble10mg/mL (clear solution) | [form ]
powder | [pka]
12.54±0.70(Predicted) | [color ]
white to beige | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. | [InChI]
1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26) | [InChIKey]
XQJWTJLJEYIUDZ-UHFFFAOYSA-N | [SMILES]
Clc1cccc(c1)-c2ccc(o2)C(=O)Nc3ccc(CN4CCOCC4)cc3 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-36 | [Safety Statements ]
26 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Description]
CID-2011756 (638156-11-3) is a potent and selective ATP-competitive inhibitor of protein kinase D (PKD). IC50=3.2, 0.6 and 0.7 μM for PKD1, 2 and 3 respectively. Inhibits phorbol ester-induced PKD activation in LNCaP prostate cancer cells. Cell permeable. | [Uses]
This novel small molecule shows inhibitory activity against PKD1 which control various cellular processes and pathological conditions. | [References]
1) Sharlow et al. (2011), Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity; PLoS One, 6 e25134 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
ChemShuttle, Inc.
|
| Telephone: |
0510-83588313-811 18800520310 |
| Website: |
www.jiehuapharma.com/ |
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
| Company Name: |
SPIRO PHARMA
|
| Telephone: |
|
| Website: |
www.spiropharma.com.cn |
|