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63824-12-4

63824-12-4 Structure

63824-12-4 Structure
IdentificationBack Directory
[Name]

aliconazole
[CAS]

63824-12-4
[Synonyms]

aliconazole
1-[(Z)-2,4-Dichloro-β-(4-chlorophenyl)cinnamyl]-1H-imidazole
1-[(Z)-2-(4-Chlorophenyl)-3-(2,4-dichlorophenyl)-2-propenyl]-1H-imidazole
1H-Imidazole, 1-[(2Z)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)-2-propen-1-yl]-
[EINECS(EC#)]

264-498-3
[Molecular Formula]

C18H13Cl3N2
[MDL Number]

MFCD00865587
[MOL File]

63824-12-4.mol
[Molecular Weight]

363.67
Chemical PropertiesBack Directory
[Boiling point ]

545.0±50.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

6.76±0.12(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Aliconazole is an antifungal imidazole derivative.
[in vivo]

Aliconazole was previously in phase III clinical trials for the determination of efficacy in the topical treatment of cutaneous fungal infections. The proposed use includes superficial fungal infections, including dermatomycoses, tinea versicolor, and cutaneous and vaginal candidiasis[1].

[storage]

Store at -20°C
[References]

[1] Fromtling RA, et al. Overview of medically important antifungal azole derivatives. Clin Microbiol Rev. 1988 Apr;1(2):187-217. DOI:10.1128/CMR.1.2.187
Spectrum DetailBack Directory
[Spectrum Detail]

aliconazole(63824-12-4)1HNMR
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