| Identification | Back Directory | [Name]
DIOFENOLAN | [CAS]
63837-33-2 | [Synonyms]
cga059205 DIOFENOLAN Diofenolan solution diofenolan (bsi,iso) Diofenolan Solution, 100ppm Diofenolan Solution in Acetonitrile, 1000μg/mL 2-ethyl-4-((4-phenoxyphenoxy)methyl)-1,3-dioxolane 1,3-Dioxolane, 2-ethyl-4-[(4-phenoxyphenoxy)methyl]- DIOFENOLAN MIXTURE OF DIASTEREO-MERS, PE STANAL, 250 MG (2S,4R)-2-ETHYL-4-[(4-PHENOXYPHENOXY)METHYL]-1,3-DIOXOLANE | [Molecular Formula]
C18H20O4 | [MDL Number]
MFCD01863142 | [MOL File]
63837-33-2.mol | [Molecular Weight]
300.35 |
| Chemical Properties | Back Directory | [Melting point ]
25°C | [Boiling point ]
361.58°C (rough estimate) | [density ]
1.0947 (rough estimate) | [refractive index ]
1.4230 (estimate) | [Fp ]
114 °C | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Oil | [color ]
Colourless to Light Yellow | [Henry's Law Constant]
1.5×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | [EPA Substance Registry System]
Diofenolan (63837-33-2) |
| Hazard Information | Back Directory | [Description]
Form: Colorless liquid | [Uses]
Diofenolan is a pesticide, an insect growth regulator. Diofenolan has been developed as a Juvenile hormone agonist for insect pest control | [Production Methods]
Diofenolan is commercially synthesised through a process begins with the preparation of a 4-phenoxyphenol intermediate, which is reacted with a chloromethyl-substituted 1,3-dioxolane under basic conditions to form the ether linkage. This reaction typically uses solvents like dichloromethane and bases such as potassium carbonate, with temperature control to ensure regioselectivity and minimize side reactions. | [Mechanism of action]
Insect growth retardant, moulting inhibitor with juvenile hormone activity | [Toxicity evaluation]
Acute oral LD50 for rats: >5,000 mg/kg | [Pesticide Type]
Insecticide; Insect Growth Regulator |
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