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64285-06-9

64285-06-9 Structure

64285-06-9 Structure
IdentificationBack Directory
[Name]

(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
[CAS]

64285-06-9
[Molecular Formula]

C10H15NO
[MDL Number]

MFCD00673924
[MOL File]

64285-06-9.mol
[Molecular Weight]

165.23
Chemical PropertiesBack Directory
[Occurrence]

An oily alkaloid, anatoxin-a has been isolated from Anabaena jfos-aquae.
[alpha ]

D25 +39.8°
[Boiling point ]

293.09°C (rough estimate)
[density ]

1.0203 (rough estimate)
[refractive index ]

1.5200 (estimate)
[storage temp. ]

Desiccate at +4°C
[pka]

9.4(at 25℃)
Hazard InformationBack Directory
[Uses]

(+)-Anatoxin-a is a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and New Zealand. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis.
[Biological Activity]

A potent nicotinic agonist (K i values are 1.25 and 1840 nM for α 4 β 2 and α 7 nicotinic receptors respectively). Stimulates [ 3 H]-dopamine release from rat striatal synaptosomes (EC 50 = 136 nM).
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
[Signal word ]

Warning
[Hazard statements ]

H361-H302+H312+H332
[Precautionary statements ]

P201-P202-P281-P308+P313-P405-P501
[Toxicity]

LD50 i.p. in mice: 200 mg/kg (Carmichael)
Questions And AnswerBack Directory
[Acute toxicity]

Intraperitoneal-mouse LDL0: 0.25 mg/kg
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