ChemicalBook--->CAS DataBase List--->64679-65-8

64679-65-8

64679-65-8 Structure

64679-65-8 Structure
IdentificationBack Directory
[Name]

5-methyl-1H-1,2,4-triazol-s-yl)thio}-acetic acid
[CAS]

64679-65-8
[Synonyms]

Nsc78999
Tiazotic acid
3-Methyl-1,2,4-triazolil-5-thioacetate
2-((5-Methyl-4H-1,2,4-triazol-3-yl)thio)acetate
5-methyl-1H-1,2,4-triazol-s-yl)thio}-acetic acid
2-(5-methyl-1H-1,2,4-triazol-3-ylthio)aceticacid
[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetic acid
2-(5-Methyl-2H-1,2,4-triazol-3-ylthio)acetic acid
2-(5-methyl-4H-1,2,4-triazol-3-ylthio)acetic acid
[(5-Methyl-1H-1,2,4-triazol-3-yl)thio]-acetic acid
Aceticacid, [(5-Methyl-1H-1,2,4-triazol-3-yl)thio]-
Acetic acid, 2-[(3-methyl-1H-1,2,4-triazol-5-yl)thio]-
[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetic acid(SALTDATA: FREE)
[(5-methyl-1H-1,2,4-triazol-3-yl)thio]acetic acid(SALTDATA: FREE)
[Molecular Formula]

C5H7N3O2S
[MDL Number]

MFCD03247350
[MOL File]

64679-65-8.mol
[Molecular Weight]

173.19
Chemical PropertiesBack Directory
[Melting point ]

226℃
[Boiling point ]

462.8±47.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

2-8°C, stored under nitrogen
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

3.13±0.10(Predicted)
[color ]

White to Off-White
Safety DataBack Directory
[REACH Registrations]

Active
[HazardClass ]

IRRITANT
Hazard InformationBack Directory
[Uses]

Tiazotic acid is a metabolic agent that has immunomodulatory, anti-inflammatory, antioxidant, anti-ischemic, cardio- and endothelioprotective, antiplatelet, hepatoprotective activities. Tiazotic acid increases the levels of eNOS. Tiazotic acid also reduces the level of D-dimer in the blood, which reduces the risks of heart attacks and strokes in post-COVID syndrome[1].
[References]

[1] Belenichev I, et al. Therapy of post-COVID-19 syndrome: improving the efficiency and safety of basic metabolic drug treatment with tiazotic acid (thiotriazoline)[J]. Pharmacia, 2022, 69: 509-516.
Spectrum DetailBack Directory
[Spectrum Detail]

5-methyl-1H-1,2,4-triazol-s-yl)thio}-acetic acid(64679-65-8)1HNMR
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