64854-64-4

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64854-64-4 Structure

Identification	Back Directory
[Name] (D-ALA2 N-ME-PHE4 MET(O)5-OL) ENKEPHALIN
[CAS] 64854-64-4
[Synonyms] san33-824 sandoz33-824 sandozfk33-824 FK 33-824, DAMME [D-Ala2,MePhe4,Met(O)5]enkephalinol (1s)-finyl)propyl)-n(supalpha)-methyl Tyr-D-Ala-Gly-(N-Methyl-Phe)-Met(O)-ol (D-ALA2 N-ME-PHE4 MET(O)5-OL) ENKEPHALIN [D-Ala(2), MePhe(4), Met(o)ol(5)]-enkephalin DAMME, FK33-824, Tyr-D-Ala-Gly-(N-Methyl-Phe)-Met(O)-ol l-phenylalaninamide,l-tyrosyl-d-alanylglycyl-n-(1-(hydroxymethyl)-3-(methylsul L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-N-[(1S)-1-(hydroxymethyl)-3-(methylsulfinyl)propyl]-NH2 L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-[(1S)-1-(hydroxymethyl)-3-(methylsulfinyl)propyl]-Nα-methyl- L-Tyrosyl-D-alanylglycyl-N-[(1S)-1-(hydroxymethyl)-3-(methylsulfinyl)propyl]-Nalpha-methyl-L-phenylalaninamide (D-Ala2,N-Me-Phe4,methionin(O)-ol5)-Enkephalin trifluoroacetate salt H-Tyr-D-Ala-Gly-N-Me-Phe-methionin(O)-ol trifluoroacetate salt
[Molecular Formula] C29H41N5O7S
[MDL Number] MFCD00076420
[MOL File] 64854-64-4.mol
[Molecular Weight] 603.73

Chemical Properties	Back Directory
[Boiling point ] 1033.4±65.0 °C(Predicted)
[density ] 1.302
[storage temp. ] −20°C
[pka] 9.97±0.15(Predicted)
[Sequence] Tyr-dAla-Gly-MePhe-Met(O)-ol

Hazard Information	Back Directory
[Description] Damme is a stable synthetic analog of methionine enkephalin. Actions are similar to those of methionine enkephalin. It can be reversed by narcotic antagonists such as naloxone. It is one of the best-known analogs that has undergone fairly extensive clinical testing.
[Uses] (D-Ala2,N-Me-Phe4,methionin(O)-ol5)-Enkephalin Trifluoroacetate Salt H-Tyr-D-Ala-Gly-N-Me-Phe-Methionin(O)-ol Trifluoroacetate Salt used in preparation of opioid peptide-endocannabinoid conjugates for treatment of neuronal disorders.

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