| Identification | Back Directory | [Name]
(32)-3,25-Dihydroxycholest-5-en-7-one | [CAS]
64907-23-9 | [Synonyms]
(32)-3,25-Dihydroxycholest-5-en-7-one
(3β)-3,25-Dihydroxycholest-5-en-7-one
(3Β)-3,25-DIHYDROXYCHOLEST-5-EN-7-ONE | [Molecular Formula]
C27H44O3 | [MDL Number]
MFCD01310734 | [MOL File]
64907-23-9.mol | [Molecular Weight]
416.636 |
| Chemical Properties | Back Directory | [Melting point ]
169-173°C | [Boiling point ]
550.2±33.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.68±0.70(Predicted) | [color ]
White to Pale Yellow |
| Hazard Information | Back Directory | [Uses]
(3β)-3,25-Dihydroxycholest-5-en-7-one is a useful synthetic intermediate in the synthesis of 3β,7α,25-Trihydroxycholest-5-ene (T795075); a potent agonist of GPR183 that induces specific activation of the receptor. | [Definition]
ChEBI: 7-keto-25-hydroxycholesterol is an oxysterol, a 7-oxo steroid, a cholestanoid, a 3beta-sterol and a 3beta-hydroxy-Delta(5)-steroid. | [Biological Activity]
7-keto-25-hydroxycholesterol (7k25OHC) might interact with the cysteine-rich domain (CRD) of the smoothened (Smo) in the hedgehog pathway. However7-keto-25-OHC is incapable of activating Smo. |
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