| Identification | Back Directory | [Name]
mebanazine | [CAS]
65-64-5 | [Synonyms]
Actamol Actomol Astomol mebanazine Mebanazina Mebenazine Einecs 200-615-6 2126-84-3 (Oxalate) 3979-76-8 (Monosulfate) α-Methylbenzylhydrazine (1-Phenylethyl)hydrazine 1-(α-Methylbenzyl)hydrazine Hydrazine, (1-phenylethyl)- (alpha-Methylbenzyl)hydrazine Hydrazine, (alpha-methylbenzyl)- Hydrazine, (1-phenylethyl)- (9ci) 1-Phenylethylhydrazine
DISCONTINUED. Please see M200450. | [EINECS(EC#)]
200-615-6 | [Molecular Formula]
C8H12N2 | [MDL Number]
MFCD00128878 | [MOL File]
65-64-5.mol | [Molecular Weight]
136.19 |
| Chemical Properties | Back Directory | [Melting point ]
169-170 °C | [Boiling point ]
240.49°C (rough estimate) | [density ]
0.9672 | [refractive index ]
1.5436 | [pka]
7.06±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Mebanazine-d5 is the labeled analogue of Mebanazine (M200450), an antidepressant agent. | [Definition]
ChEBI: Mebanazine is a member of benzenes. | [in vivo]
Mebanazine (90 mg/kg; i.p.; once; mature female rats) decreases the blood giucose level[1].
Mebanazine (1-60 mg/kg; i.p.; once; mature female rats) has the minimal dose which lowered blood glucose after 12 h is 60 mg/kg[1].
| Animal Model: | Mature female rats[1] | | Dosage: | 90 mg/kg | | Administration: | Intraperitoneal injection; once | | Result: | Decreased the blood giucose level after 4-8 h, and continues for 2 days. |
| Animal Model: | Mature female rats[1] | | Dosage: | 0-60 mg/kg | | Administration: | Intraperitoneal injection; once | | Result: | Decreased the blood giucose level in a dose-dependent manner. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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