ChemicalBook--->CAS DataBase List--->65043-60-9

65043-60-9

65043-60-9 Structure

65043-60-9 Structure
IdentificationBack Directory
[Name]

Lup-20(29)-en-16-one, 3-hydroxy-, (3β)-
[CAS]

65043-60-9
[Synonyms]

3β-Hydroxy-lup-20(29)-en-16-one
Lup-20(29)-en-16-one, 3-hydroxy-, (3β)-
[Molecular Formula]

C30H48O2
[MOL File]

65043-60-9.mol
[Molecular Weight]

440.71
Chemical PropertiesBack Directory
[Boiling point ]

516.0±50.0 °C(Predicted)
[density ]

1.017±0.06 g/cm3(Predicted)
[pka]

15.18±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

3β-Hydroxy-lup-20(29)-en-16-one (compound 9) is a dual inhibitor of AChE and BChE, with selectivity for BChE (IC50: 28.9 μM)[1].
[References]

[1] Castro MJ, et al. Oxidation at C-16 enhances butyrylcholinesterase inhibition in lupane triterpenoids. Bioorg Chem. 2018 Sep;79:301-309. DOI:10.1016/j.bioorg.2018.05.012
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