| Identification | Back Directory | [Name]
N-{[(4-{[(3,4-dimethylphenyl)amino]sulfonyl}phenyl)amino]carbonothioyl}-3-phenylpropanamide | [CAS]
650621-20-8 | [Synonyms]
PTP1B-IN-13
N-({4-[(3,4-dimethylphenyl)sulfamoyl]phenyl}carbamothioyl)-3-phenylpropanamide
Benzenepropanamide, N-[[[4-[[(3,4-dimethylphenyl)amino]sulfonyl]phenyl]amino]thioxomethyl]-
N-{[(4-{[(3,4-dimethylphenyl)amino]sulfonyl}phenyl)amino]carbonothioyl}-3-phenylpropanamide | [Molecular Formula]
C24H25N3O3S2 | [MOL File]
650621-20-8.mol | [Molecular Weight]
467.6 |
| Hazard Information | Back Directory | [Uses]
PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM. | [References]
[1] Yang Y, et al. Integrated Approach to Identify Selective PTP1B Inhibitors Targeting the Allosteric Site. J Chem Inf Model. 2021 Sep 27;61(9):4720-4732. DOI:10.1021/acs.jcim.1c00357 |
|
|