| Identification | Back Directory | [Name]
(S)-4,11-Bis(((butoxycarbonyl)amino)methyl)-10-carboxy-5-oxo-2,4,6,11,13-pentaazatetradecanedioic acid, 1,14-dibutyl ester | [CAS]
65132-74-3 | [Synonyms]
(S)-4,11-Bis(((butoxycarbonyl)amino)methyl)-10-carboxy-5-oxo-2,4,6,11,13-pentaazatetradecanedioic acid, 1,14-dibutyl ester | [Molecular Formula]
C30H57N7O11 | [MOL File]
65132-74-3.mol | [Molecular Weight]
691.814 |
| Hazard Information | Back Directory | [Description]
A 924 is an antineoplastic amino acid derivative. | [Uses]
A 924 is an amino acid derivative-based, orally active antitumor agent. A 924 is effective in inhibiting ascites tumors in rat models by intraperitoneal injection or oral administration. The LD50 of A 924 in mice is >1.5 g/kg and >4.5 g/kg by intraperitoneal injection or oral administration, respectively. A 924 does not cause teratogenicity or adverse reactions in normal or pregnant mice[1]. | [References]
[1] Fujita H, et al. A new antineoplastic amino acid derivative, A-924. Cancer Treat Rep. 1977 Nov;61(8):1577-8. PMID:200358 |
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