| Identification | Back Directory | [Name]
7-Fluoro-7-deaza-2'-deoxyadenosine | [CAS]
652965-07-6 | [Synonyms]
2’-Deoxy-7-fluo rotubercidin
7-Fluoro-7-deaza-2'-deoxyadenosine
7-deaza-7-fluoro-2'-deoxyadenosine
2’-Deoxy-7-fluo rotubercidin,7-Fluoro-7-deaza-2’-deoxyadenosine
7-Fluoro-7-deaza-2'-deoxyadenosine4-Amino-5-fluoro-7-(2-deoxy--D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
2'-Deoxy-7-fluoro-tubercidin, 7-Fluoro-7-deaza-2’-deoxyadenosine, 4-Amino-5-fluoro-7-(2-deoxy-?-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine | [Molecular Formula]
C11H13FN4O3 | [MDL Number]
MFCD32670233 | [MOL File]
652965-07-6.mol | [Molecular Weight]
268.25 |
| Chemical Properties | Back Directory | [Melting point ]
165 °C(Solv: dichloromethane (75-09-2); methanol (67-56-1)) | [Boiling point ]
603.1±55.0 °C(Predicted) | [density ]
1.84±0.1 g/cm3(Predicted) | [pka]
13.26±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1]. | [References]
[1] Galmarini CM, et al. Pyrimidine nucleoside analogs in cancer treatment. Expert Rev Anticancer Ther. 2003 Oct;3(5):717-28. DOI:10.1586/14737140.3.5.717 |
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