| Identification | Back Directory | [Name]
1-methoxyphaseollidin | [CAS]
65428-13-9 | [Synonyms]
1-methoxyphaseollidin
6H-Benzofuro[3,2-c][1]benzopyran-3,9-diol, 6a,11a-dihydro-1-methoxy-10-(3-methyl-2-buten-1-yl)-, (6aR,11aR)- | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C21H22O5 | [MDL Number]
MFCD32644958 | [MOL File]
65428-13-9.mol | [Molecular Weight]
354.4 |
| Chemical Properties | Back Directory | [Boiling point ]
521.7±50.0 °C(Predicted) | [density ]
1.270±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
9.15±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3]. | [Definition]
ChEBI: 1-Methoxyphaseollidin is a member of pterocarpans. | [IC 50]
Human Endogenous Metabolite | [References]
[1] Fukai T, et, al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 Aug 9;71(12):1449-63. DOI:10.1016/s0024-3205(02)01864-7
[2] Nagumo S, et, al. Inhibition of lysoPAF acetyltransferase activity by components of licorice root. Biol Pharm Bull. 1999 Oct;22(10):1144-6. DOI:10.1248/bpb.22.1144
[3] Sinha SK, et, al. Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies. Comb Chem High Throughput Screen. 2021;24(4):591-597. DOI:10.2174/1386207323999200817103148 |
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| Company Name: |
BioBioPha Co., Ltd.
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0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
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