| Identification | Back Directory | [Name]
Sclerotigenin | [CAS]
65641-84-1 | [Synonyms]
Sclerotigenin
6,7-dihydro-quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
Quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione, 6,7-dihydro-
6,7-dihydro-6,8,13a-triaza-benzo[3,4]cyclohepta[1,2-b]naphthalene-5,13-dione | [Molecular Formula]
C16H11N3O2 | [MDL Number]
MFCD33021324 | [MOL File]
65641-84-1.mol | [Molecular Weight]
277.28 |
| Chemical Properties | Back Directory | [Melting point ]
235-238 °C | [density ]
1.45±0.1 g/cm3(Predicted) | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
11.90±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
Sclerotigenin is a natural diazepine originally isolated from P. sclerotigenum that acts as an insect growth regulator. It reduces the growth rate of first instar H. zea larvae by 42% relative to controls when administered in the standard test diet at 200 ppm. | [Uses]
Sclerotigenin is an anti-insect benzodiazepine compound identified in Penicillium sclerotigenum (NRRL 3461). Sclerotigenin exhibits significant anti-insect activity against crop pest Helicoverpa zea[1]. | [References]
[1] Joshi BK, et al. Sclerotigenin: A new antiinsectan benzodiazepine from the sclerotia of penicillium sclerotigenum. J Nat Prod. 1999 Apr;62(4):650-2. DOI:10.1021/np980511n |
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