ChemicalBook--->CAS DataBase List--->66-28-4

66-28-4

66-28-4 Structure

66-28-4 Structure
IdentificationBack Directory
[Name]

STROPHANTHIDIN
[CAS]

66-28-4
[Synonyms]

corchorin
cynotoxin
nsc-86078
Corcholin
cyanotoxin
cymarigenin
CYMARIGENEN
Corchotoxin
apocynamarin
corchorgenin
corchsularin
erysimupikron
Corchorogenin
Strophantidin
erysimupicrone
STROPHANTHIDIN
antibioticxs-89
strophanthidine
K-STROPHANTHIDIN
STROPHANTHIDIN K
STIGMASTANOL(SH)
convallatoxigenin
k-strophanthidine
20(22)-cardenolide
corchosideaaglycon
3β,5,14-Trihydroxy-19-oxo-5β
5-beta-hydroxy-19-oxodigitoxigenin
3,5,14-trihydroxy-19-oxocard-20(22)-enolide
3-beta,5,14-trioxy-19-oxo-digen-(20:22)-olid
3-beta,5,14-trioxy-19-oxo-carden-(20:22)-olid
19-oxo-cardogenen-(20:22)-triol-(3-beta,5,14)
3β5,14-Trihydroxy-19-oxo-5β20(22)-cardenolide
5BETA,20[22]-CARDENOLIDE-19-ONE-3BETA,5,14-TRIOL
3BETA,5,14-TRIHYDROXY-19-OXO-5BETA,20[22]-CARDENOLIDE
3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolid
3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolide
(3beta,5beta)-3,5,14-trihydroxy-19-oxocard-20(22)-enolide
3,5,14-trihydroxy-19-oxo-,(3-beta,5-beta)-card-20(22)-enolid
3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Cymarigenen, K-Strophanthidin
Strophanthidin,3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Cymarigenen, K-Strophanthidin
(3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
(3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-17-(5-keto-2H-furan-3-yl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
[EINECS(EC#)]

200-626-6
[Molecular Formula]

C23H32O6
[MDL Number]

MFCD00046266
[MOL File]

66-28-4.mol
[Molecular Weight]

404.5
Chemical PropertiesBack Directory
[Melting point ]

169°C
[alpha ]

D25 +43.1° (c = 2.8 in methanol)
[Boiling point ]

446.1°C (rough estimate)
[density ]

1.432±0.06 g/cm3 (20 ºC 760 Torr)
[refractive index ]

1.4593 (estimate)
[storage temp. ]

−20°C
[solubility ]

ethanol: complete50mg/mL, clear, colorless to yellow
[form ]

Solid
[pka]

13.92±0.70(Predicted)
[color ]

White to off-white
[optical activity]

+43.125 (c 2.8, methanol)
Hazard InformationBack Directory
[Uses]

cardiotonic
[Definition]

ChEBI: Strophanthidin is a 3beta-hydroxy steroid, a 14beta-hydroxy steroid, a 5beta-hydroxy steroid, a 19-oxo steroid, a member of cardenolides and a steroid aldehyde. It is functionally related to a 5beta-cardanolide.
[General Description]

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
[Biochem/physiol Actions]

Strophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes.1 It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.2
Safety DataBack Directory
[Hazard Codes ]

T+
[Risk Statements ]

26/27/28
[Safety Statements ]

22-36/37/39-45
[RIDADR ]

UN 2811 6.1/PG 1
[WGK Germany ]

3
[RTECS ]

FH5425000
[Toxicity]

LD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel)
Spectrum DetailBack Directory
[Spectrum Detail]

STROPHANTHIDIN(66-28-4)IR1
STROPHANTHIDIN(66-28-4)IR2
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